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Regenerative Medicine

Regenerative medicine uses cutting-edge technology to help your body rebuild damaged cells, tissues, or organs.

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About Regenerative Medicine:

The human body has an innate power to heal itself. When you cut your skin, bruise your tissue or break a bone, the body’s natural wisdom takes over, and in time the body will reorganize, repair, and regenerate itself, usually back to normal given the right conditions and environment. 


What is Regenerative Medicine?

Regenerative Medicine capitalizes and builds on this natural process within the realm of disease.

This branch of medicine is pioneering in the way we view and treat diseases. Instead of approaching treatment from the perspective of disease management, Regenerative Medicine seeks to find innovative solutions to restore the structure and function of damaged organs or tissues. Thus, it seeks to find a cure for otherwise untreatable injuries or diseases and return the body to full health and vitality. It potentially holds the key to treating what have so far been classed as untreatable ailments or situations, such as major traumas where organs are lost or damaged beyond repair. In the instance of organ regeneration, this branch of medicine has the capability to short-circuit donor availability and post-transport immune complications.


Regenerative medicine includes the generation and use of therapeutic stem cells, tissue engineering, and the production of artificial organs. Techniques include using materials and newly generated cells to take the place of the missing tissue, replacing it structurally and functionally, or contributing to tissue healing. More specific examples include cell therapies (injection of stem cells), immunomodulation therapy (regeneration by biologically active molecules administered alone or as secretions by infused cells), and tissue engineering (transplantation of laboratory-grown organs and tissues).


What differentiates regenerative medicine from standard pharmacological interventions is that drugs used in disease management primarily target symptoms, whereas regenerative medicine focuses on treating the root cause of a disease condition by replacing lost biomaterials, cells or organs, or fixing a faulty gene.



Examples of regenerative medicine

  • Stem cell therapies

This involves the use of stem cells in our bodies. The body uses stem cells to repair and replace some cells or organs within the body. Stem cells can be derived from bone marrow, blood, adipose (fat), skeletal muscle, cord blood, dental pulp, and other bodily sources. There are millions of stem cells within our body. When these stem cells are harvested and reinjected into treatment sites, tissues in the treatment sites begin to undergo reconstruction and repair under favorable conditions. 

Factors that can affect the effectiveness of stem cell therapy include the severity of the condition or injury, aging, the type of stem cells collected, and lifestyle habits.

  • Tissue Engineering and Biomaterials

Tissue engineering involves the assembling, construction, and use of materials that are compatible with the biological makeup of different parts of the body. These materials are then injected or placed in sites where they help restore, maintain, or improve damaged tissues or organs. Examples of biomaterials include gelatin, collagen, metals, glass, silk, polymers, and ceramics seen in items like pacemakers, heart valves, contact lenses, and orthopedic devices.

  • Medical devices and artificial organs

In cases where an organ fails and other factors like delay in getting a donor, or time for the donor to meet requirements for organ harvesting, this form of regenerative medicine comes to play. Medical devices and artificial organs can be used in the interim before an organ is found and transplanted. Others are used as replacements. Many of these devices have been used for body organs like the heart, lung, liver, pancreas, limbs, and kidneys. Examples include artificial heart and pacemakers, dialysis machines, prostheses, etc.

  • Cartilage regeneration

People with musculoskeletal conditions can benefit from this form of regenerative medicine, particularly people aged 55 and above. Cartilage does not contain blood vessels; hence poor blood supply impairs its healing. Cartilage regeneration helps heal damaged cartilage.

  • Prolotherapy

This is often used for people with joint and muscle pain. It involves injecting a natural irritant solution into the soft tissue of a joint, ligaments, and/or tendons to stimulate growth in the connective tissue of the joint. This new growth helps to treat pain and inflammation. It is often used to treat low back pain and other joint injuries. It is also known as regenerative injection therapy or proliferation therapy.

  • Platelet-rich plasma (PRP) therapy

This form of regenerative therapy uses a centrifuged blood fraction that is concentrated in platelets derived from a patient to treat and heal injured joints, ligaments, muscles, and tendons. It is also sued to treat hair loss.

What conditions can regenerative medicine help to treat?

Regenerative medicine has been researched widely and can be used to treat a variety of treatments. Some of these conditions include: 

  • Autoimmune diseases such as lupus, rheumatoid arthritis, Crohn’s disease, amyotrophic lateral sclerosis,
  • Spinal cord injury and nerve damage
  • Neurodegenerative diseases such as Alzheimer’s disease, Parkinson’s disease,
  • Orthopedic conditions such as osteoarthritis, bursitis, plantar fasciitis, herniated discs, disc degeneration and tears, damaged ligaments, tendon tears and tendinitis, carpal tunnel syndrome, golfer’s elbow, tennis elbow, etc.
  • Aging features such as wrinkles,
  • Hair loss
  • Erectile dysfunction
  • Type 1 diabetes
  • Cardiovascular disease including heart disease, stroke,
  • Cancer such as lymphoma, leukemia, 
  • Burns
  • Chronic obstructive pulmonary disease (COPD)
  • Sport injuries


How effective is regenerative medicine in treating chronic conditions?

The earliest forms of regenerative medicine were blood transfusions which have successfully saved lives over the years and are now a very common therapy offered in healthcare facilities. Also, regenerative therapies are known to provide a faster healing process than conventional methods of treatment.

According to a trial, stem cell therapy achieved positive outcomes in over 45% of patients. Patients experienced significant improvements in less than 6 months as opposed to back surgery which takes longer recovery periods.

In another study, stem cell therapy provided acceptable functional results for stress urinary incontinence (SUI) in both male and female patients. Side-effects and complications recorded were minimal as well.

Platelet-rich plasma is one of the modalities in regenerative medicine. According to a study among patients with chronic plantar fasciitis, PRP injection was safe and yielded positive results without any complications. Most patients reported pain relief and reduction in functional limitations. In a similar study, PRP injections were also said to reduce pain and inflammation associated with osteoarthritis. Also, knee functional status significantly improved in patients who received PRP injections.

Prolotherapy in a study involving the use of intra-articular dextrose injections reported pain relief, improved function, and quality of life in patients with knee osteoarthritis. The therapy was described as straightforward, safe, and yielded high adherence and satisfaction among patients.


Is regenerative medicine appropriate for anyone?

Depending on the type of regenerative therapy to be provided, not anyone can undergo regenerative medicine procedures.

You may not be able to have a stem cell transplant if you have:

  • Genetic disorders such as cystic fibrosis, neurofibromatosis, muscular dystrophy, and tuberous sclerosis.
  • Systemic infection
  • Cancer
  • HIV infection
  • Metabolic disorders or mitochondrial dysfunction
  • Hepatitis- HBV, HCV
  • End organ damage
  • Epilepsy
  • Psychological factors that affect your ability to adhere to the treatment and follow-up requirements.

For platelet-rich plasma (PRP) therapy and prolotherapy, people with the following conditions cannot receive or benefit from PRP injections:

  • Have a medical condition that could get worse or spread with injections. Examples include active infection, local abscess, cellulitis, septic arthritis, certain skin diseases, or metastatic cancer.
  • Have certain blood or bleeding disorders
  • Have systemic infection
  • Are on anticoagulation medication
  • Are anemic
  • Have non-musculoskeletal pain
  • Have chemical dependence
  • Have morbid obesity
  • Have a low pain threshold

Generally, any condition or factor that will affect compatibility, adherence to pre- and post-treatment requirements, and follow-up should be considered a contraindication.

Are regenerative medicine treatments covered by insurance?

The simple yet frustrating answer to this question is “it depends”. Insurance companies generally do not pay the cost of regenerative therapies including stem cell treatments, platelet-rich plasma (PRP) therapy, organ transplant, etc. These therapies are often considered as “fee for service” type of treatments. Insurance companies, however, may pay consultation fees and other associated costs incurred during the procedure. 

Medicare, however, covers part of the cost of stem cell therapies for FDA-approved treatments, that is allogeneic hematopoietic stem cell transplantation (Allo-SCT) and autologous stem cell transplantation (Au-SCT). Some other companies may cover cortisone injections and other related options that may help your treatment.

Regenerative medicine can be effective for a whole range of health challenges, including dermal wounds, organ failure, cardiovascular diseases, traumas, and treatments for cancers as well as tissues or organs damaged by age, disease, trauma, and regulate congenital defects. If you are suffering from a condition or disease which is otherwise untreatable, regenerative medicine might just be the progressive approach you need. Our practitioners are able to expertly guide you through new terrain and provide ongoing support. 

As our approach at Wisdom is integrative, holistic, and functional, you’ll also have access to additional complementary therapies to enhance your healing and guide you towards optimal wellbeing. Your quality of life will be radically improved, even whilst receiving treatment. You’ll feel fully educated and empowered in the trajectory of your treatment, healing, and health.


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